GD
← Back to index

Google DeepMind

AI research systems for mathematics, biology, weather and materials.

Related updates

Major milestones over time

Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub

From the Bitter Lesson of AI scaling to the unsolved mysteries of protein folding , Google DeepMind’s Pushmeet Kohli and Biohub’s Sal Candido are rethinking what it takes to build AI that truly understands biology. In this special panel moderated by Brandon Anderson , they explore why AlphaFold’s breakthrough was only the beginning , why scaling compute and data alone won’t solve biology, and how the next generation

View original ↗

Google DeepMind and Meta Join Biohub's $1.8 Billion AI Biology Push

Alphabet (GOOGL) and Meta Platforms (META) are buying into AI biology. On Wednesday, October 7, Google DeepMind, Alphabet’s drug discovery unit Isomorphic Labs, and Meta agreed to put a combined $300 million into Biohub’s Virtual Biology Initiative. Biohub is the science group backed by Mark Zuckerberg and Priscilla Chan. With the U.S. Department of Energy and the National Institutes of Health also in, total commitme

View original ↗

Google DeepMind creates watermarked AI-designed proteins that still work in lab tests

Google DeepMind creates watermarked AI-designed proteins that still work in lab tests SynthID Bio embeds a detectable signature into AI-generated protein sequences and structures, with Nature research showing the watermark can survive without significantly disrupting biological function Google DeepMind researchers have demonstrated a way to watermark AI-designed proteins while preserving their biological function, an

View original ↗

Google DeepMind watermarks AI-designed proteins, and the first binders still bind

Google DeepMind watermarks AI-designed proteins, and the first binders still bind Google DeepMind has taken its SynthID watermark into biology, and says the first watermarked protein binders still bind. In wet-lab testing against three target proteins, VEGF-A, the SARS-CoV-2 spike protein RBD and PD-L1, the watermarked designs “matched the hit rate, binding affinity, and natural sequence diversity of unwatermarked ve

View original ↗

Google DeepMind publishes SynthID Bio, a watermarking method for AI-designed proteins

In what can be called a major breakthrough for synthetic biology and AI-powered biosecurity, Google DeepMind, Google’s AI lab, has developed a new method to watermark AI-designed proteins, establishing a permanent proof of origin directly inside biological code. Published in the journal Nature, the proof-of-concept technology, which is named SynthID Bio, solves a long-standing technical challenge: embedding an non-no

View original ↗

Introducing SynthID Bio: Google DeepMind Puts Watermarks Inside AI-Designed Proteins

Introducing SynthID Bio: Google DeepMind Puts Watermarks Inside AI-Designed Proteins Google DeepMind is introducing SynthID Bio after laboratory tests produced the first watermarked protein binders that retained their intended biological function. The September 30 announcement moves AI watermarking beyond images, text, audio, and video. Its signature can remain detectable in a synthesized physical protein, not merely

View original ↗

Google DeepMind develops invisible watermarks for AI-designed proteins

October 1, 2026 report Google DeepMind develops invisible watermarks for AI-designed proteins Paul Arnold Author Gaby Clark Scientific Editor Robert Egan Senior Editor Watermarks have long protected everything from bank notes and fine art to digital photographs and software, helping prove authenticity and trace an object's origin. Their main function is to protect copyright and verify authenticity. That same traceabi

View original ↗

Google DeepMind Introduces SynthID Bio for Watermarking AI-Designed Proteins

Introducing SynthID Bio Proof of concept for watermarking AI-generated proteins while preserving biological function. Today, we’re introducing SynthID Bio to bring watermarking technology to synthetic biology. SynthID Bio embeds an imperceptible signature directly into the biological code, ensuring the watermark is verifiable not just on a digital model but on the synthesized, physical protein itself – all while pres

View original ↗

PhysBrain 1.5 Tops Open-Source Models on 28 Public Benchmarks, Nears GPT-6 Astra

The report says the Chinese company DeepCybo released the physical foundation model PhysBrain 1.5 on September 9, 2026. It scored 72.5 on 28 public benchmarks, ranking first among participating open-source models, with 14 first-place and 10 second-place open-source results. Its score is within 1 point of GPT-6 Astra (73.3) and Gemini 3.6 Flash (73.0), and above Hy-Embodied-VLM-1.0 (66.0) by about 6.5 points and RynnB

View original ↗

Google DeepMind maps 9 billion DNA mutations: how AI could help solve rare diseases

Google DeepMind has created an AI-powered map of about 9 billion possible single-letter changes in human DNA, giving scientists a new way to search for genetic mutations that could matter for disease and biology. Called AlphaGenome Atlas, the platform contains precomputed predictions for every possible single-nucleotide variant in the human genome. DeepMind says testing billions of possible changes individually in la

View original ↗

AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome

AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome How predicting the molecular impact of every possible single-letter DNA variant in the human genome will help accelerate our understanding of biology. Today, we are introducing AlphaGenome Atlas: a platform (detailed in our paper) containing predictions for the effects of 9 billion single-nucleotide variants — every single-let

View original ↗

Google DeepMind publishes AI-powered predictions for effect of all 9B mutations to human DNA

Google DeepMind said Tuesday that it has used artificial intelligence to predict the biological consequences of all 9 billion possible single-letter changes to human DNA, and is making the resulting database available free to academic researchers worldwide. AlphaGenome Atlas, as DeepMind calls the database, is a precomputed catalogue of what each substitution of a single DNA base is likely to do to the machinery that

View original ↗

Introducing WeatherNext 3, our most advanced and accurate global weather AI model

Introducing WeatherNext 3, our most advanced and accurate global weather AI model Every day, the weather influences billions of decisions. Some are as simple as grabbing an umbrella before heading out the door, but others are far more consequential. Wind, rain, and extreme weather events, like heatwaves and droughts, have cascading impacts across agriculture, global supply chains, clean energy production, and nationa

View original ↗

KAIST Unveils Korean AlphaFold-Style Bio-AI Model K-Fold

The analysis speed is up to 25 times faster Strategic technology to escape under Big Tech Bio-artificial intelligence (AI), such as Google DeepMind's "Alpha Fold 3," which won the 2024 Nobel Prize in Chemistry, has also emerged in Korea. The speed of predicting protein structure and designing new drug candidates is the fastest in the world. KAIST, the organizer of the 'AI-specific foundation model project' promoted b

View original ↗

AINews: 10% worse, 100x cheaper, 10000x faster: Why Simulation is taking over

According to Latent Space, since 2022, components of the AI pipeline have been shifting from human-made to model-made, each flip starting with a 'patient zero' at a frontier lab. This trend is characterized as simulation: slightly worse (10%), but 100x cheaper and 10,000x faster. Stage 1 (2022): Reward signal went synthetic with InstructGPT's reward model, followed by Constitutional AI and RLAIF, where AI critiques i

View original ↗

Pushmeet Kohli on AlphaEvolve and AI's Scientific Revolution

DeepMind’s Pushmeet Kohli on AI’s Scientific Revolution Pushmeet Kohli leads AI for Science at DeepMind, where his team has created AlphaEvolve, an AI system that discovers entirely new algorithms and proves mathematical results that have eluded researchers for decades. From improving 50-year-old matrix multiplication algorithms to generating interpretable code for complex problems like data center scheduling, AlphaE

View original ↗

WeatherNext: AI model achieves breakthrough in forecasting cyclones

WeatherNext: AI model achieves breakthrough in forecasting cyclones WeatherNext enables accurate cyclone forecasts that can give an extra day of warning. Now we are open sourcing the model. Predicting how dangerous cyclones develop is a longstanding challenge where every hour counts. Tropical cyclones — also known as hurricanes or typhoons — are among the most destructive weather phenomena on Earth, responsible for m

View original ↗

Accelerating Scientific Discovery: Google's $40M Commitment to the Genesis Mission

Accelerating the frontiers of scientific discovery: Google’s $40M commitment to the Genesis Mission Pushmeet Kohli VP for Science and Strategic Initiatives, Google DeepMind, and Chief Scientist, Google Cloud Karthik Narain Chief Product and Business Officer, Google Cloud Google AI for Public Sector Empowering an Adaptive, Responsible, Secure, and Intelligent way forward Learn more Scientists today face challenges of

View original ↗

Patrick Hsu: How Is AI Catalyzing Life Science?

“The future of biology is programmable.” To give you a sense of how important this topic is, Patrick Hsu is the first guest we’ve had back to Ground Truths since the podcast began a few years ago. Nearly 2 years ago we spoke about digital biology but so much has happened since to help unravel the complexities in the language of life. Patrick is a co-founder and core investigator at the Arc Institute . His work is at

View original ↗

Our approach to bioresilience

Our approach to bioresilience The global biosecurity landscape is rapidly evolving. Shifting natural ecosystems, global travel and the potential misuse of AI require greater vigilance — yet AI is also a critical tool for our response. We need frontier AI models, and the scientific advances they will enable, to respond to these challenges and help make society more resilient to events like future outbreaks. Today, Goo

View original ↗

Conjecture Machines: AI agents and the new validation bottleneck in science

Conjecture Machines: AI agents and the new validation bottleneck in science Over the past year, agents have transformed what it means to code. Scientific research may be next — from proposing novel hypotheses, to designing experiments, to discovering algorithms that improve on the best that humans have designed. This raises urgent questions for policymakers and science funders, the biggest being how to validate the c

View original ↗

Our 2025 Annual Report: A Year of Momentum for Interspecies Understanding

Our 2025 Annual Report The past few years have seen a steady drumbeat of discoveries that illustrate the complex communications and culture of other animals, many of them accelerated by significant advances in technology. We are proud to be part of this incredible progress in understanding our fellow species. Our 2025 Annual Report highlights the advances we’ve made with our partners over the past year in the burgeon

View original ↗

AlphaFold v3.0.3 Release Notes

Version 3.0.3 changes the AlphaFold 3 code license from CC BY-NC-SA 4.0 to Apache 2.0. Moreover, it provides bug fixes and a performance improvement for large inputs. We thank everyone who reported issues, proposed new features, and submitted PRs! Change log Below is a selection of new features, performance improvements and bug fixes. Full change log: v3.0.2...v3.0.3 New features AlphaFold 3 is now compatible with Py

View original ↗

CZ Biohub releases “ESM Atlas” with 1.1 billion ESMFold2-predicted protein structures, claiming to surpass AlphaFold

A claim has emerged that a new protein structure prediction artificial intelligence (AI) model surpasses the performance of Google DeepMind’s AlphaFold, which was developed by DeepMind and even led to the 2024 Nobel Prize in Chemistry. Experts are divided between seeing it as an important new resource for protein structure prediction and expressing doubts about its performance. According to a report in the internatio

View original ↗

Farewell to External AI Models

Machine learning (ML) models have become an increasingly important component of the global weather forecasting landscape. Over the past few years at ECMWF, several externally developed models have been run alongside the Integrated Forecasting System (IFS) in an experimental setting, allowing their performance to be assessed against established numerical methods. The upgrade of the IFS to Cycle 50r1 has provided a tes

View original ↗

Demis Hassabis on AlphaFold as the First Rung of AI-Driven Science

Demis Hassabis, CEO of Google DeepMind and 2024 Nobel laureate in Chemistry, has spent the first months of 2026 articulating a specific and measurable thesis: AlphaFold, the protein-structure model that now serves more than three million researchers across 190 countries, is the first rung in an AI-powered scientific revolution, not the last. His clearest statement of this position came in a Semafor interview publishe

View original ↗

Vivek Natarajan of Google DeepMind to Speak at RAAIS 2026

The Research and Applied AI Summit (RAAIS) is a community for entrepreneurs and researchers who accelerate the science and applications of AI technology. In the run up to our 10th annual event on June 12th 2026 in London, we’re running a series of speaker profiles to shed more light on what you can expect to learn on the day! Vivek Natarajan is a Research Lead at Google DeepMind leading research at the intersection o

View original ↗

10 Years of AlphaGo

Demis Hassabis traces how AlphaGo's search and learning ideas fed into AlphaFold, AlphaProof, AlphaEvolve and the broader scientific-AI program.

View original ↗

Gemini Deep Think: Redefining the Future of Scientific Research

Accelerating Mathematical and Scientific Discovery with Gemini Deep Think Under direction from expert mathematicians and scientists, Gemini Deep Think is solving professional research problems across mathematics, physics, and computer science In the summer of 2025, an advanced version of Gemini Deep Think achieved Gold-medal standard at the International Mathematics Olympiad (IMO) and later, an updated version, obtai

View original ↗

Formalization of Erdős Problems

[This is a guest post by Boris Alexeev . Now over to Boris.] I’m here to tell you about various exciting developments centering on Erdős problems, especially involving the formalization of old and new mathematics using artificial intelligence. Background As is well known, Paul Erdős was a prolific mathematician of the 20th century who posed an extraordinary number of conjectures. Around May 2023 , Thomas Bloom set up

View original ↗

Google DeepMind and Fields Medalist Terence Tao Detail AI-Powered Mathematical Discoveries with AlphaEvolve

Google DeepMind’s AlphaEvolve AI is accelerating mathematical research at an unprecedented scale, according to a new paper published this week by collaborators including renowned mathematician Terence Tao. The research shows how the AI agent tackled 67 challenging problems, rediscovering top solutions and finding novel constructions for several long-standing challenges. The work demonstrates a powerful new method for

View original ↗