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AlphaFold 3 Releases

AlphaFold v3.0.3 Release Notes

Summary

Version 3.0.3 changes the AlphaFold 3 code license from CC BY-NC-SA 4.0 to Apache 2.0. Moreover, it provides bug fixes and a performance improvement for large inputs. We thank everyone who reported issues, proposed new features, and submitted PRs! Change log Below is a selection of new features, performance improvements and bug fixes. Full change log: v3.0.2...v3.0.3 New features AlphaFold 3 is now compatible with Python 3.14. The AlphaFold 3 code is now relicensed from CC BY-NC-SA 4.0 to Apache 2.0. Performance improvements Confidences JSON serialization is up to 30x faster, for a 5,000-residue input the serialization time drops 43 -> 1.3 s. mmCIF parsing is 4% faster. Bug fixes A new flag was introduced to not drop O1 atom from non-linking saccharides/glycans. Thanks @magnusbauer and @Jonas-Wilhelm . Added support for dynamic version (inferred from the commit history) for dev and releases. Thanks @ccoulombe . Pass all flags correctly to Jackhmmer/Nhmmer. Thanks @chenbq18 . Fix glycan O1 leaving-atom cleanup for standalone glycans. Thanks @Jonas-Wilhelm and @magnusbauer . Do not drop chain descriptions for RNA and protein chains. Thanks @ntnn19 . Fixes of typing issues revealed by Pyrefly. Documentation Fixed typos in docstrings, thanks @mooreneural . We thank the following people for their pull requests and/or great suggestions: @ccoulombe , @Jonas-Wilhelm , @magnusbauer , @mooreneural , @ntnn19 .

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AlphaFold 3 Releases
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github.com
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