A knowledge-driven framework for predicting single-cell responses for unprofiled drugs
Summary
Nature Machine Intelligence, Published online: 26 August 2026; doi:10.1038/s42256-026-01286-w Feng et al. introduce MAP, an artificial intelligence framework that integrates biological mechanism knowledge to predict how cells respond to chemical perturbation, improving generalization to untested drugs and prioritizing cancer drug candidates in virtual screening.
Evidence & checks
- Discovery channel
- Nature Portfolio · Nature Machine Intelligence
- Original material
- www.nature.com
- Material type
- Source page; material type not verified
- Material basis
- Retrieval basis unknown
- Review status
- No human-review record